The Ultimate Guide to Under-Eye Skin Regenerative Treatments: Sunekos vs Polynucleotides vs Julaine for Dark Circles & Crepey Skin

Dark circles, crepey under-eye skin, and tired-looking eyes are among most peoples to aesthetic concerns. The under-eye area has extremely thin skin and limited collagen and it is often the first place to show ageing, dehydration, and loss of elasticity. Whilst great eye cream can certainly improve skin quality and should always be used to boost and maintain an clinical treatments, it may not be enough to tackle more visible signs of aging or pigmentation, particualry as we pass beyond our 30s.

Recently there have been a great increase in skin regenerative treatments for under-eye rejuvenation — including Sunekos, polynucleotide injections, and Julaine — and these are transforming how we treat dark circles, fine lines, and under-eye crepiness.

If you’ve been searching for the best treatment for dark circles under the eyes, this comprehensive comparison breaks down exactly what each treatment does, how they differ, and which one may suit your concerns best.

Why Under-Eye Regenerative Treatments Are Gaining Popularity

Unlike fillers, which add volume, regenerative under-eye treatments focus on improving the quality of the skin itself. These biostimulating injections work by stimulating collagen, elastin, cellular repair, and hydration — biologically restoring the delicate under-eye area from within.

This makes them ideal for:

• Dark circles (vascular, structural, or thin-skin related)

• Crepey skin under the eyes

• Fine lines and wrinkles

• Dull, tired-looking eyes

• Dehydration and skin laxity

• Thin or fragile under-eye skin

  
  

Treatment Breakdown

1. Sunekos for Under-Eye Darkness & Crepiness

Sunekos is a great biostimulator for under-eye skin rejuvenation, combining hyaluronic acid + amino acids to stimulate collagen and elastin production. Both It's widely used as a non-filler dark circle treatment for those wanting subtle, natural rejuvenation.

How Sunekos Works

• Boosts fibroblast activity

• Regenerates collagen and elastin

• Improves dermal density and elasticity

• Deeply hydrates without adding volume

  
  

Best For

✔ Mild to moderate dark circles

✔ Under-eye crepey skin

✔ Fine lines and early ageing

✔ “Tired eye” appearance

✔ Those avoiding filler

Sunekos is ideal for natural-looking under-eye rejuvenation with minimal downtime and gradual improvement.

2. Polynucleotide Injections for Dark Circles & Thin Under-Eye Skin

Polynucleotides (PN/PDRN) are among the most advanced skin regenerative treatments available today. These DNA-based injections repair tissue at a cellular level and are particularly powerful for dark circles caused by thin skin, shadowing, or vascular issues.

How Polynucleotides Work

• Stimulate deep cellular repair

• Improve microcirculation (helping reduce vascular dark circles)

• Increase collagen and elastin production

• Enhance hydration and dermal thickness

• Strengthen thin or fragile under-eye skin

  
  

Best For

✔ Dark circles from thin skin or visible vessels

✔ Moderate crepiness and skin laxity

✔ Inflammed, eczema or dermatitis prone skin and eyes

✔ Under-eye dullness

✔ Anyone wanting long-term regenerative results

Polynucleotides are extremely popular for advanced dark circle treatment and for individuals with crepey, fragile under-eye skin who want a natural, refreshed look.

3. Julaine

Julaine is a new PLLA biodermal activator that provides intense collagen regeneration and skin repair that can be used all over the face and body. Unlike older PLLA treatments such as Sculptra, Julaine is great to use around the eyes to help firm skin, reduce laxity, provide structure without volume and aid mild volume loss.

How Julaine

• Causes PLLA lactic acid to stimulate type 1 collagen synthesis and skin repair

• Regeration occurs for 18 months post initial course of treatment

• Restores skin strength and firmness

• Collagen production achieves a lifted appearance to skin and face without using filler

• Improves brightness, texture, and elasticity

• Reduces under-eye shadows, crows feet and fine lines

  
  

Best For

✔ Mild to moderate dark circles

✔ Crows feet and ifine lines

✔ Under-eye hollowness without willer

✔ Those wanting to avoid or minimise teartrough filler and dermal filler use

✔ Those wanting a gentle, gradual yet effective refresh

Which Treatment Should You Choose?

The Future of Dark Circle Treatments Is Regenerative

Sunekos, Polynucleotides, and Julainehave changed the landscape of non-surgical under-eye rejuvenation, offering powerful skin regenerative treatments that target the root causes of dark circles, crepey skin, and under-eye ageing.

These treatments don’t just mask concerns — they repair, restore, and rebuild the under-eye skin from deep within. Even though they all offer great benefit, an examination adn consultation will allow Dr Anatalia to recommend the best treatment for your needs.