How to Treat Winter Skin Inflammation: The Best Treatments for Rosacea, Sensitivity & Acne
- dranataliamoore
- 3 days ago
- 4 min read

Why Winter Worsens Inflammatory Skin Conditions
During colder months, the skin barrier becomes weaker, leading to:
Increased transepidermal water loss (TEWL)
Reduced collagen and elastin production
Heightened sensitivity and redness
Slower skin repair and healing
This creates the perfect storm for conditions such as:
Rosacea flare-ups
Inflamed or cystic acne
Dry, dehydrated and flaky skin
Eczema-prone or reactive skin
Winter can be one of the most challenging seasons for skin health. Cold temperatures, low humidity, indoor heating and reduced barrier function often trigger inflammatory skin conditions such as rosacea, inflamed acne, dryness and dehydration. For many patients, winter also accelerates visible signs of ageing, leaving skin dull, sensitive and compromised. Whilst you definately should look to ensure your skincare at home delivers hydration as well as contains antiinflammatory actives, it may not be enough or you may want to boost results.
What is the best skin treatment for rosacea, inflamed skin, sensitive skin and angry breakouts?
One of the most advanced regenerative treatments in aesthetic medicine today—polynucleotides—offers a powerful solution. Clinically proven to repair, hydrate and calm inflamed skin, polynucleotides are fast becoming the gold-standard injectable treatment for winter skin concerns, while also delivering impressive anti-ageing benefits.
What Are Polynucleotides? Are polynucleotides salmon sperm
Polynucleotides are classed as regenerative skin treatments; biostimulatory injectable treatments derived from purified DNA fragments. Unlike traditional dermal fillers, they do not add volume. Instead, they work at a cellular level to regenerate and restore skin health from within. Whilst you may have heard of salmon sperm facials, don’t worry, it isn’t actually this we inject, it is simply purified DNA fragments derived from this. These switch on cellular repair mechanisms on many levels.
How Polynucleotides Work: The Mechanism of Action

Polynucleotides act as powerful bio-regenerators, delivering multiple benefits simultaneously:
1. Cellular Repair & Regeneration
Polynucleotides stimulate fibroblast activity, the cells responsible for producing collagen, elastin and hyaluronic acid. This leads to stronger, healthier skin over time and is why they are great to firm up delicate skin such as under the eyes or along neck or forehead lines.
2. Anti-Inflammatory Action
They help modulate inflammatory pathways, significantly reducing redness, irritation and sensitivity—making them ideal for rosacea, senstive and dry as well as and inflamed acne.
3. Improved Microcirculation
Enhanced blood flow improves oxygen and nutrient delivery to the skin, accelerating healing and restoring vitality so healing skin on all levels.
4. Deep Hydration & Barrier Repair
Polynucleotides bind water within the skin and support barrier recovery, addressing chronic dryness and dehydrationcommon in winter.
5. Protection Against Oxidative Stress
They neutralise free radicals, helping protect skin from environmental damage and premature ageing.
What is the best treatment for Rosacea?
Polynucleotides for Rosacea and Redness
For patients struggling with rosacea, polynucleotides offer a gentle yet highly effective treatment option that:
Calms chronic inflammation
Reduces flushing and redness
Strengthens fragile capillaries
Improves skin tolerance and resilience
Unlike aggressive treatments that may exacerbate rosacea, polynucleotides work in harmony with sensitive skin, making them suitable for even the most reactive patients.
What is the best treatment for acne?
Treating Inflamed Acne Without Drying the Skin
Winter acne often presents as inflamed, painful breakouts, particualry after the indulgences and lifestyle changes of party season and this is worsened when combined with dryness from harsh products or cold weather.
Polynucleotides help by:
Reducing inflammatory acne lesions
Supporting wound healing and scar prevention
Regulating skin repair without stripping hydration
Improving post-inflammatory redness
This makes them an excellent alternative or adjunct to traditional acne therapies, particularly for adult or sensitive acne sufferers.
What is the best treatment for dry and inflammed skin?
The Ultimate Solution for Dry and Dehydrated Winter Skin
If your skin feels tight, dull or flaky despite using moisturisers, the issue often lies deeper than the surface.
Polynucleotides:
Restore hydration at a cellular level
Repair a compromised skin barrier
Improve skin elasticity and comfort
Leave skin plump, luminous and resilient
They are particularly effective for patients whose skin cannot tolerate strong actives or exfoliation during winter.
How do polynucleotides help skin?
Beyond treating inflammatory skin conditions, polynucleotides are also a powerful anti-ageing treatment.
With consistent treatments, patients can expect:
Improved skin texture and tone
Increased collagen and elastin production
Reduced fine lines and crepiness
Enhanced skin firmness and elasticity
A healthy, youthful glow
This makes polynucleotides ideal for preventative ageing and for patients seeking natural, regenerative results rather than volume enhancement.
The best Winter Skin Treatments
Polynucleotides and their antiinflammatory and hydratign benefits make them ideal treatments to sooth winter skin concerns.
✔ Suitable for sensitive and compromised skin✔ Minimal downtime and low risk of irritation✔ Safe for face, neck, eyes and décolletage✔ Can be combined with other aesthetic treatments✔ Strengthens skin long-term, not just temporarily
Are Polynucleotides Right for You?
Polynucleotides are suitable for:
Rosacea-prone or sensitive skin
Inflammatory or adult acne
Dry, dehydrated or winter-damaged skin
Early signs of ageing
Patients seeking natural skin regeneration
If you are not seeing results from skincare alone
A personalised consultation ensures the treatment is tailored to your skin’s unique needs.
How to Restore, Repair and Rejuvenate Your Skin This Winter
If winter has left your skin inflamed, dry or prematurely aged, polynucleotide treatment offers a science-backed solution that works from the inside out.
By calming inflammation, restoring hydration and stimulating regeneration, polynucleotides don’t just treat symptoms—they transform skin health and they work far beyond the under eye area!
Book a consultation at our Manchester skin, wellness and aesthetics clinic today and discover how polynucleotides can help your skin thrive all winter long







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