What Is Inflammaging? How Chronic Inflammation Affects Your Skin — And the Treatments & Wellness Strategies That Help You Age Well

Wellness, Skin & Aesthetic Clinic – Manchester

INFLAMMAGING can sneak up on us

You may be doing seemingly “all the right things” — using active skincare, booking facials, eating relatively well — and yet your skin feels more reactive, looks duller, or seems to be ageing faster than it should.

This is where inflammaging comes in.

What Is Inflammaging?

Inflammaging describes chronic, low-grade inflammation in the body and skin that gradually accelerates the ageing process.

Unlike acute inflammation — which helps heal a wound or fight infection — chronic inflammation is subtle and persistent. It keeps the body, mind and skin in a constant state of defence.

Over time, this disrupts repair processes, weakens collagen and elastin, alters pigment behaviour and compromises the skin barrier.

The result?

• Acne flares

• Rosacea flare-ups

• Increased sensitivity

• Pigmentation changes

• Fine lines

• Laxity

• Dull, uneven texture

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When damage outweighs the skin’s ability to repair, visible ageing accelerates.

What Triggers Inflammaging?

Inflammation can be driven by:

• Sleep deprivation

• Chronic stress, even low level

• Nutrient deficiencies

• Blood sugar imbalance

• UV exposure

• Pollution

• Overuse of active skincare

• Harsh cleansing products

• Impaired gut health

Individually these may seem minor. Cumulatively, they place the skin under constant strain.

The Skin Barrier: Your First Line of Defence

One of the most overlooked aspects of inflammaging is barrier disruption.

When the barrier is compromised:

• Water loss increases

• Sensitivity worsens

• Inflammatory mediators rise

• Repair slows down

This is why clever, streamlined skincare is more effective than overwhelming 10-step routines.

In-Clinic Treatments That Support Inflammaging — The Regenerative Approach

When addressing inflammaging, the goal isn’t to freeze or simply fill. It’s to nourish the body and skin, calm inflammation, restore healthy cell signalling and stimulate regeneration.

At our Manchester clinic, we focus on treatments that work with your bodie’s internal health, your mental wellbeing and your skin’s biology.

LED Light Therapy

Clinically proven red, near-infrared and blue wavelengths help:

• Reduce inflammatory cytokines

• Support collagen synthesis

• Improve healing

• Softens & prevents lines, laxity and wrinkles

• Calm rosacea, acne, dermatitis and reactive skin

• Balance the skin microbiome

  
  

LED works at a cellular level by supporting mitochondrial energy production and reducing oxidative stress — without damaging the barrier.

Polynucleotides

Polynucleotides are advanced regenerative injectables that:

• Down-regulate inflammatory signals

• Stimulate fibroblast activity

• Improve tissue repair

• Strengthen the extracellular matrix

• Ultimately hydrating, calming, brigthening and strengthening skin

They are particularly effective for delicate, sun-damaged or rosacea-prone skin where chronic inflammation has impaired healing.

Amino Acid Treatments (e.g. Sunekos)

Amino acid treatments such as Sunekos provide the essential building blocks needed for collagen and elastin production.

They:

• Support fibroblast function

• Improve elasticity and density

• Enhance hydration

• Promote natural regeneration

Ideal when skin appears tired, crepey or inflamed but doesn’t require structural volume correction.

PLLA Biostimulators (e.g. Julaine)

PLLA treatments such as Julaine stimulate gradual collagen renewal.

They work by:

• Encouraging controlled collagen production

• Improving firmness over time

• Strengthening tissue structure

• Counteracting collagen breakdown caused by chronic inflammation

This is about rebuilding quality and resilience — not creating artificial fullness.

Far Beyond a Quick Fix 💪

Whilst inflammaging may be the current buzzword, optimising internal health and skin health is not a trend — it’s an ongoing strategy.

The best and most lasting results come from:

• Cumulative small healthy habits tailored to you

• Achievable and sustainable lifestyle choices

• Combination targeted regenerative treatments

• Clever, streamlined, barrier-supportive skincare

Not overwhelm. Not extremes. Not chasing every new product launch.

Patience & Knowledge Are Key

Inflammaging develops gradually — and reversing its visible effects requires time, consistency and strategy.

But you can make a difference.

With the right support, a detailed consultation and follow up so we really get to know you, targetted blood testing and bespoke wellness and age-well treatment plan it is absolutely possible to:

• Reduce chronic inflammation through the whole body

• Strengthen the skin barrier

• Stimulate collagen

• Improve firmness and tone

• Slow accelerated ageing

  
  

Ready to Address Inflammaging Properly?

If your skin feels reactive, tired or older than it should — it may be time to look beneath the surface.

Reach out.Visit our website and blog for more education.Or book your consultation to create a personalised plan tailored to your skin and lifestyle.

Because quick fixes fade.But informed, regenerative care delivers lasting change